ATP-dependent membrane remodeling links EHD1 functions to endocytic recycling

The GTPase dynamin catalyzes membrane fission but activity of the dynamin-related ATPase EHD1 is unknown. Here, using in vitro reconstitution assays and molecular dynamics simulations, the authors report that EHD1 hydrolyzes ATP to remodel, causing fission of membrane tubes and that this is necessar...

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Bibliografske podrobnosti

Principais autores:	Raunaq Deo, Manish S. Kushwah, Sukrut C. Kamerkar, Nagesh Y. Kadam, Srishti Dar, Kavita Babu, Anand Srivastava, Thomas J. Pucadyil
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2018-12-01
Serija:	Nature Communications
Online dostop:	https://doi.org/10.1038/s41467-018-07586-z
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