Epigenome-Wide Association Studies of the Fractional Exhaled Nitric Oxide and Bronchodilator Drug Response in Moderate-to-Severe Pediatric Asthma

Asthma is the most prevalent pediatric chronic disease. Bronchodilator drug response (BDR) and fractional exhaled nitric oxide (FeNO) are clinical biomarkers of asthma. Although DNA methylation (DNAm) contributes to asthma pathogenesis, the influence of DNAm on BDR and FeNO is scarcely investigated....

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Hoofdauteurs:	Mario Martin-Almeida, Javier Perez-Garcia, Esther Herrera-Luis, Carlos Rosa-Baez, Mario Gorenjak, Anne H. Neerincx, Olaia Sardón-Prado, Antoaneta A. Toncheva, Susanne Harner, Christine Wolff, Susanne Brandstetter, Elisa Valletta, Mahmoud I. Abdel-Aziz, Simone Hashimoto, Vojko Berce, Paula Corcuera-Elosegui, Javier Korta-Murua, Heike Buntrock-Döpke, Susanne J. H. Vijverberg, Joris C. Verster, Nikki Kerssemakers, Anna M Hedman, Catarina Almqvist, Jesús Villar, Aletta D. Kraneveld, Uroš Potočnik, Michael Kabesch, Anke H. Maitland-van der Zee, Maria Pino-Yanes, on behalf of the SysPharmPediA Consortium
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2023-02-01
Reeks:	Biomedicines
Onderwerpen:	epigenetic biomarker methylation asthma FeNO BDR
Online toegang:	https://www.mdpi.com/2227-9059/11/3/676
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