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A novel method for sensitive and specific detection of DNA methylation biomarkers based on DNA restriction during PCR cycling

DNA methylation is an important epigenetic mechanism involved in fundamental biological processes such as development, imprinting, and carcino-genesis. For these reasons, DNA methylation represents a valuable source for cancer biomarkers. Methods for the sensitive and specific detection of methylate...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Christoph Kneip, Bernd Schmidt, Michael Fleischhacker, Anke Seegebarth, Jörn Lewin, Nadja Flemming, Stefanie Seemann, Thomas Schlegel, Christian Witt, Volker Liebenberg, Dimo Dietrich
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis Group 2009-09-01
Seri Bilgileri:BioTechniques
Konular:
DNA methylation
quantitative real-time PCR
sensitive detection
diagnostics
cancer
early detection
Online Erişim:https://www.future-science.com/doi/10.2144/000113208
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