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The JNK pathway is a key mediator of Anopheles gambiae antiplasmodial immunity.

The innate immune system of Anopheles gambiae mosquitoes limits Plasmodium infection through multiple molecular mechanisms. For example, midgut invasion by the parasite triggers an epithelial nitration response that promotes activation of the complement-like system. We found that suppression of the...

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Bibliografiske detaljer
Principais autores: Lindsey S Garver, Giselle de Almeida Oliveira, Carolina Barillas-Mury
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2013-01-01
Serier:PLoS Pathogens
Online adgang:http://europepmc.org/articles/PMC3764222?pdf=render
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