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Competing Genetic Traits and Their Influence on LDL Cholesterol Concentration in Familial Hypercholesterolemia

Familial hypercholesterolemia is a monogenic disorder that leads to premature atherosclerosis as a result of lifelong exposure to elevated low-density lipoprotein cholesterol (LDL-C). Both genetic traits and lifestyle factors can influence LDL-C levels. Adults with LDL-C of 170 mg/dL and higher may...

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Main Authors: Christopher Song, MD, Robert S. Rosenson, MD
Format: Artigo
Language:Inglês
Published: Elsevier 2024-01-01
Series:JACC: Case Reports
Subjects:
familial hypercholesterolemia
PCSK9 deficiency
Online Access:http://www.sciencedirect.com/science/article/pii/S2666084923005272
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