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PRKAA2 mediates the pathogenesis of metabolic dysfunction-associated steatotic liver disease via PI3K/AKT signaling pathway

Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most prevalent type of chronic liver disease, posing a significant threat to human health. Protein kinase AMP-activated catalytic subunit alpha 2 (PRKAA2) plays a pivotal role in regulating metabo...

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Main Authors: Jiayi Li, Guiling Wu, Zihao Li, Xinghuan Liang, Yiyu Chen, Bing Yang, Jing Xian, Tingting Deng, Cuihong Chen, Li Li, Yang Liu, Tian Xiong, Sihui Wu, Xi Yang, Yingfen Qin
Format: Artigo
Language:Inglês
Published: BMC 2025-11-01
Series:Human Genomics
Subjects:
PRKAA2
Signaling pathway
miRNA
MASLD
Pathogenesis
Online Access:https://doi.org/10.1186/s40246-025-00854-2
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