A deeper evaluation of cytokeratin fragment 21-1 as a lung cancer tumor marker and comparison of different assays

Studies show CYFRA 21-1 fragments of cytokeratin 19 (CK19) to be promising biomarkers for non-small cell lung cancer (NSCLC). Although previous literature identifies specific CYFRA 21-1 antibody binding epitopes, the exact molecular weight of the CK19 fragment being detected by current assays is not...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Dianna J. Rowe, Timothy A. Khalil, Michael N. Kammer, Caroline M. Godfrey, Yong Zou, Cindy L. Vnencak-Jones, David Xiao, Stephen Deppen, Eric L. Grogan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2025-05-01
Schriftenreihe:	Biosensors and Bioelectronics: X
Schlagworte:	CYFRA 21-1 Biomarker Enzyme-linked immunosorbent assay (ELISA) Chemiluminescent assay (ChLIA) Electrochemiluminescence immunoassay (ECLIA) Compensated interferometric reader (CIR)
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2590137025000202
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