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Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD.

DNA damage recognition by the nucleotide excision repair pathway requires an initial step identifying helical distortions in the DNA and a proofreading step verifying the presence of a lesion. This proofreading step is accomplished in eukaryotes by the TFIIH complex. The critical damage recognition...

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Auteurs principaux: Stefanie C Wolski, Jochen Kuper, Petra Hänzelmann, James J Truglio, Deborah L Croteau, Bennett Van Houten, Caroline Kisker
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2008-06-01
Collection:PLoS Biology
Accès en ligne:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.0060149&type=printable
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