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African swine fever virus hijacks host pyrimidine metabolism to promote viral replication

ABSTRACT African swine fever (ASF) is a highly contagious disease of pigs caused by the African swine fever virus (ASFV), posing a significant threat to global swine production. As an obligate intracellular parasite, ASFV relies on host metabolic networks to fulfill its replication requirements. How...

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Principais autores: Zebu Song, Yilin Chen, Hui Guo, Guihong Zhang, Lang Gong, Zezhong Zheng
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2025-11-01
Serier:Journal of Virology
Fag:
African swine fever virus
pyrimidine metabolism
glutamine
aspartate
metabolic hijacking
Online adgang:https://journals.asm.org/doi/10.1128/jvi.00985-25
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