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Sprouting Angiogenesis in Human Pituitary Adenomas

IntroductionAngiogenesis in pituitary tumors is not fully understood, and a better understanding could help inform new pharmacologic therapies, particularly for aggressive pituitary tumors.Materials and Methods219 human pituitary tumors and 12 normal pituitary glands were studied. Angiogenic genes w...

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Autori principali: Jie Zhou, Yaomin Hu, Wende Zhu, Chuansheng Nie, Wenxiu Zhao, Alexander T. Faje, Kay E. Labelle, Brooke Swearingen, Hang Lee, E. Tessa Hedley-Whyte, Xun Zhang, Pamela S. Jones, Karen K. Miller, Anne Klibanski, Yunli Zhou, Roy J. Soberman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-05-01
Serie:Frontiers in Oncology
Soggetti:
sprouting angiogenesis
angiogenic gene expression
angiogenesis inhibition
endothelial marker
Rb1 mice
VEGF inhibitor
Accesso online:https://www.frontiersin.org/articles/10.3389/fonc.2022.875219/full
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