A diverse repertoire of CD4 T cells targets the immediate-early 1 protein of human cytomegalovirus

T cell responses to the immediate-early 1 (IE-1) protein of human cytomegalovirus (HCMV) are associated with protection from viral disease. Thus, IE-1 is a promising target for immunotherapy. CD8 T cell responses to IE-1 are generally strong. In contrast, CD4 T cell responses to IE-1 were described...

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Detalhes bibliográficos

Principais autores:	Stefanie eAmeres, Xiaoling eLiang, Martina eWiesner, Josef eMautner, Andreas eMoosmann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2015-11-01
coleção:	Frontiers in Immunology
Assuntos:	Cytomegalovirus HLA-DR hcmv CD4 T cells HLA-DQ HLA class II
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00598/full
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