414 Leveraging modular TriKE-PACC molecules capable of dual-antigen targeting to enhance NK-cell immunotherapy in AML.

Objectives/Goals: Acute myeloid leukemia (AML) is an aggressive blood cancer that hides from the immune system, which led to ~140,000 deaths worldwide in 2024. AML often recurs or resists therapy; therefore, our goal is to develop and test TriKE-PACCs, which combine dual tumor antigen targeting with...

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Hauptverfasser:	Anders Matson, Caden Caligiuri, Katherine M. Koehler, Behiye Kodal, Emma M Eungard, Yvette Soignier, Samreen Fathima, Jeffrey S. Miller, Martin Felices
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cambridge University Press 2026-04-01
Schriftenreihe:	Journal of Clinical and Translational Science
Online-Zugang:	https://www.cambridge.org/core/product/identifier/S2059866126105664/type/journal_article
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