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Targeting SETDB1 in cancer and immune regulation: Potential therapeutic strategies in cancer

Abstract SET domain bifurcated histone lysine methyltransferase 1 (SETDB1/ESET), a pivotal H3K9 methyltransferase, has been extensively studied since its discovery over two decades ago. SETDB1 plays critical roles in immune regulation, including B cell maturation, T‐cell activity modulation, and end...

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Bibliografski detalji
Glavni autori: Bo‐Syong Pan, Cheng‐Yu Lin, Gilbert Aaron Lee, Hui‐Kuan Lin
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2025-03-01
Serija:Kaohsiung Journal of Medical Sciences
Teme:
Online pristup:https://doi.org/10.1002/kjm2.12933
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