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Fluorine labelling of therapeutic human tolerogenic dendritic cells for 19F-magnetic resonance imaging

Tolerogenic dendritic cell (tolDC) therapies aim to restore self-tolerance in patients suffering from autoimmune diseases. Phase 1 clinical trials with tolDC have shown the feasibility and safety of this approach, but have also highlighted a lack of understanding of their distribution in vivo. Fluor...

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Principais autores: Fiona Cooke, Mary Neal, Matthew J. Wood, I. Jolanda M. de Vries, Amy E. Anderson, Julie Diboll, Arthur G. Pratt, James Stanway, Ioana Nicorescu, Nicholas Moyse, Dawn Hiles, David Caulfield, Anne M. Dickinson, Andrew M. Blamire, Pete Thelwall, John D. Isaacs, Catharien M. U. Hilkens
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-10-01
coleção:Frontiers in Immunology
Assuntos:
tolerogenic dendritic cells
19F
cell tracking
111Indium
MRI
rheumatoid arthritis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.988667/full
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