Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus.

Although disease remission can frequently be achieved for patients with neuroblastoma, relapse is common. The cancer stem cell theory suggests that rare tumorigenic cells, resistant to conventional therapy, are responsible for relapse. If true for neuroblastoma, improved cure rates may only be achie...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Yonatan Y Mahller, Jon P Williams, William H Baird, Bryan Mitton, Jonathan Grossheim, Yoshinaga Saeki, Jose A Cancelas, Nancy Ratner, Timothy P Cripe
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2009-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	http://europepmc.org/articles/PMC2626279?pdf=render
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