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Dynamic modes of Notch transcription hubs conferring memory and stochastic activation revealed by live imaging the co-activator Mastermind

Developmental programming involves the accurate conversion of signalling levels and dynamics to transcriptional outputs. The transcriptional relay in the Notch pathway relies on nuclear complexes containing the co-activator Mastermind (Mam). By tracking these complexes in real time, we reveal that t...

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Váldodahkkit: F Javier DeHaro-Arbona, Charalambos Roussos, Sarah Baloul, Jonathan Townson, María J Gómez Lamarca, Sarah Bray
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: eLife Sciences Publications Ltd 2024-05-01
Ráidu:eLife
Fáttát:
Liŋkkat:https://elifesciences.org/articles/92083
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