Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation

Summary: Activating mutations in the canonical Wnt/β-catenin pathway are key drivers of hyperplasia, the gateway for tumor development. In a wide range of tissues, this occurs primarily through enhanced effects on cellular proliferation. Whether additional mechanisms contribute to β-catenin-driven h...

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Bibliografiske detaljer

Principais autores:	Emanuele Pignatti, Sining Leng, Yixing Yuchi, Kleiton S. Borges, Nick A. Guagliardo, Manasvi S. Shah, Gerard Ruiz-Babot, Dulanjalee Kariyawasam, Makoto Mark Taketo, Ji Miao, Paula Q. Barrett, Diana L. Carlone, David T. Breault
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2020-04-01
Serier:	Cell Reports
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2211124720304241
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