KLHDC4 serves as a novel prognostic biomarker and drives tumor progression via PI3K/AKT signaling in clear cell renal cell carcinoma

Abstract The clinical significance and molecular mechanisms of KLHDC4 in malignancies, particularly in clear cell renal cell carcinoma (ccRCC), remain poorly understood. In this study, we integrated multi-omics data—including transcriptomic, proteomic, and single-cell RNA sequencing—to systematicall...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Qingjiang Xu, Weili Chen, Senming Cao, Xiubin Li, Xiang Wu, Xin Ma
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Portfolio 2026-02-01
Sarja:	Scientific Reports
Aiheet:	KLHDC4 Prognostic biomarker Clear cell renal cell carcinoma PI3K/AKT pathway
Linkit:	https://doi.org/10.1038/s41598-026-39061-x
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