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Utilisation of monoclonal antibodies in the single radial immunodiffusion assay to determine potency and stability for seasonal and pandemic influenza vaccines

IntroductionFollowing manufacture, influenza vaccines are required to undergo potency testing as part of the release process to market. The single radial immunodiffusion (SRID) assay is currently the compendial standard for determining the antigen potency and stability of protein-based influenza vac...

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Hoofdauteurs: Jesse Bodle, David Burge, Gopal Gounder, Kirsten Vandenberg, Karen Laurie, Steven Rockman
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2025-11-01
Reeks:Frontiers in Immunology
Onderwerpen:
vaccine potency
potency test
monoclonal antibody
mAb
haemagglutinin
influenza vaccine
Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1696191/full
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