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Cell Culture Process Scale-Up Challenges for Commercial-Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products

Allogeneic cell therapy products, such as therapeutic cells derived from pluripotent stem cells (PSCs), have amazing potential to treat a wide variety of diseases and vast numbers of patients globally. However, there are various challenges related to manufacturing PSCs in single-use bioreactors, par...

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Principais autores: Brian Lee, Sunghoon Jung, Yas Hashimura, Maximilian Lee, Breanna S. Borys, Tiffany Dang, Michael S. Kallos, Carlos A. V. Rodrigues, Teresa P. Silva, Joaquim M. S. Cabral
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-02-01
coleção:Bioengineering
Assuntos:
allogeneic cell therapy
induced pluripotent stem cell
human embryonic stem cell
cell aggregate
expansion
differentiation
Acesso em linha:https://www.mdpi.com/2306-5354/9/3/92
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