Design, Synthesis, and Mechanistic Study of 2-Pyridone-Bearing Phenylalanine Derivatives as Novel HIV Capsid Modulators

The AIDS pandemic is still of importance. HIV-1 and HIV-2 are the causative agents of this pandemic, and in the absence of a viable vaccine, drugs are continually required to provide quality of life for infected patients. The HIV capsid (CA) protein performs critical functions in the life cycle of H...

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Bibliografiske detaljer

Principais autores:	Xujie Zhang, Lin Sun, Shujing Xu, Xiaoyu Shao, Ziyi Li, Dang Ding, Xiangyi Jiang, Shujie Zhao, Simon Cocklin, Erik De Clercq, Christophe Pannecouque, Alexej Dick, Xinyong Liu, Peng Zhan
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2022-11-01
Serier:	Molecules
Fag:	HIV capsid phenylalanine derivatives protein-protein interaction
Online adgang:	https://www.mdpi.com/1420-3049/27/21/7640
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