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The predictive value of tumor mutation burden for immune checkpoint inhibitors therapy in non-small cell lung cancer is affected by patients’ age

Abstract High tumor mutation burden (TMB), which is associated with increased tumor immunogenicity, has been identified to predict improved response to immune checkpoint inhibitors (ICIs) therapy in non-small cell lung cancer (NSCLC). As host immunity is also significant to eliminate cancer cells, h...

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Principais autores: Yongfeng Wu, Jinming Xu, Jiawei Xu, Yiqing Wang, Luming Wang, Wang Lv, Jian Hu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-04-01
Serier:Biomarker Research
Fag:
Tumor mutation burden
TMB
Age
Immune checkpoint inhibitor
ICI
NSCLC
Online adgang:http://link.springer.com/article/10.1186/s40364-020-00188-2
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