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Quantifying 3′UTR length from scRNA-seq data reveals changes independent of gene expression

Abstract Although more than half of all genes generate transcripts that differ in 3′UTR length, current analysis pipelines only quantify the amount but not the length of mRNA transcripts. 3′UTR length is determined by 3′ end cleavage sites (CS). We map CS in more than 200 primary human and mouse cel...

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Autors principals: Mervin M. Fansler, Sibylle Mitschka, Christine Mayr
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2024-05-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-024-48254-9
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