The Role of Fatty Acid Synthase in the Vascular Smooth Muscle Cell to Foam Cell Transition

Vascular smooth muscle cells (VSMCs), in their contractile and differentiated state, are fundamental for maintaining vascular function. Upon exposure to cholesterol (CHO), VSMCs undergo dedifferentiation, adopting characteristics of foam cells—lipid-laden, macrophage-like cells pivotal in atheroscle...

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書誌詳細

主要な著者:	Bethany J. Bogan, Holly C. Williams, Claire M. Holden, Vraj Patel, Giji Joseph, Christopher Fierro, Hugo Sepulveda, W. Robert Taylor, Amir Rezvan, Alejandra San Martin
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2024-04-01
シリーズ:	Cells
主題:	VSMC phenotype fatty acid synthase (FASN) Krüppel-like factor 4 (KLF4) foam cells lipids lipid droplets
オンライン･アクセス:	https://www.mdpi.com/2073-4409/13/8/658
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