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CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis

Summary: Septic acute kidney injury (S-AKI), the most common type of acute kidney injury (AKI), is intimately related to pyroptosis and oxidative stress in its pathogenesis. Carboxy-terminus of Hsc70-interacting protein (CHIP), a U-box E3 ligase, modulates oxidative stress by degrading its targeted...

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Principais autores: Hao Zhang, Zebin Deng, Yilong Wang, Xiaoping Zheng, Lizhi Zhou, Shu Yan, Yinhuai Wang, Yingbo Dai, Yashpal.S. Kanwar, Fei Deng
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2023-10-01
סדרה:iScience
נושאים:
Nephrology
Molecular physiology
Molecular medicine
גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S2589004223018394
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