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Similar Safety Profile of the Enantiomeric N-Aminoalkyl Derivatives of <i>Trans</i>-2-Aminocyclohexan-1-ol Demonstrating Anticonvulsant Activity

Epilepsy is one of the most common neurological disorder in the world. Many antiepileptic drugs cause multiple adverse effects. Moreover, multidrug resistance is a serious problem in epilepsy treatment. In the present study we evaluated the safety profile of three (<b>1</b>&#8722;<b>3</b>) new chira...

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Principais autores: Karolina Słoczyńska, Paulina Koczurkiewicz, Kamil Piska, Beata Powroźnik, Katarzyna Wójcik-Pszczoła, Katarzyna Klaś, Magdalena Wyszkowska-Kolatko, Elżbieta Pękala
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-07-01
coleção:Molecules
Assuntos:
aminocyclohexanol
cytotoxicity
enantiomers
epilepsy
mutagenicity
P-glycoprotein
Acesso em linha:https://www.mdpi.com/1420-3049/24/13/2505
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