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NLRP3 activation promotes cGAS/STING signaling and antitumor immunity by colorectal cancer cells

Abstract Introduction Colorectal cancer (CRC) is a highly prevalent and deadly disease that is largely refractory to immunotherapy. The only CRC subset that responds to these therapies is characterized by prevalent microsatellite instability (MSI), extensive  CD8+ T cell infiltration and high expres...

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Detaylı Bibliyografya
Asıl Yazarlar: Courtney Mowat, Daniel Schiller, Kristi Baker
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer 2025-06-01
Seri Bilgileri:Cancer Immunology, Immunotherapy
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Online Erişim:https://doi.org/10.1007/s00262-025-04088-y
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