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Metformin and intermittent fasting mitigate high fat-fructose diet-induced liver and skeletal muscle injury through upregulation of mitophagy genes in rats

Abstract Background High fat-fructose diet is a proinflammatory diet that increases risk of hepatocytes and myocytes steatosis and fibrosis. Finding anti-inflammatory strategies to fight these harmful effects is paid attention to nowadays. This study compared the effects of two widely anti-inflammat...

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Principais autores: Nermeen Bastawy, Ghada Farouk Soliman, Nermeen Bakr Sadek, Doaa Mostafa Gharib, Mai Abdelaziz Gouda, Laila Ahmed Rashed, Hanan Abdallah, Dina Hisham, Omnia Mohamed Abdel-Maksoud
Formato: Artigo
Idioma:Inglês
Publicado em: SpringerOpen 2024-09-01
coleção:Beni-Suef University Journal of Basic and Applied Sciences
Assuntos:
Mitophagy
Metformin
Fasting
PINK1
PARKIN
LAMP2
Acesso em linha:https://doi.org/10.1186/s43088-024-00548-z
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