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Type VII Secretion Substrates of Pathogenic Mycobacteria Are Processed by a Surface Protease

ABSTRACT Tuberculosis, one of the world’s most severe infectious diseases, is caused by Mycobacterium tuberculosis. A major weapon of this pathogen is a unique cell wall that protects the pathogen from eradication by the immune system. Mycobacteria have specialized secretion systems, e.g., type VII...

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Principais autores: Maroeska J. Burggraaf, Alexander Speer, Aniek S. Meijers, Roy Ummels, Astrid M. van der Sar, Konstantin V. Korotkov, Wilbert Bitter, Coenraad Kuijl
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019-10-01
coleção:mBio
Assuntos:
aspartic protease
Mycobacterium
PE proteins
PE_PGRS
type VII secretion
Acesso em linha:https://journals.asm.org/doi/10.1128/mBio.01951-19
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