The evolution of resistance to synergistic multi‐drug combinations is more complex than evolving resistance to each individual drug component

Abstract Multidrug antibiotic resistance is an urgent public health concern. Multiple strategies have been suggested to alleviate this problem, including the use of antibiotic combinations and cyclic therapies. We examine how adaptation to (1) combinations of drugs affects resistance to individual d...

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Bibliografske podrobnosti

Principais autores:	Natalie Ann Lozano‐Huntelman, Austin Bullivant, Jonathan Chacon‐Barahona, Alondra Valencia, Nick Ida, April Zhou, Pooneh Kalhori, Gladys Bello, Carolyn Xue, Sada Boyd, Colin Kremer, Pamela J. Yeh
Format:	Artigo
Jezik:	Inglês
Izdano:	Wiley 2023-12-01
Serija:	Evolutionary Applications
Teme:	antibiotic combinations antibiotic resistance antimicrobial bacterial evolution
Online dostop:	https://doi.org/10.1111/eva.13608
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