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Design and rationale of the CHILL phase II trial of hypothermia and neuromuscular blockade for acute respiratory distress syndrome

The Cooling to Help Injured Lungs (CHILL) trial is an open label, two group, parallel design multicenter, randomized phase IIB clinical trial assessing the efficacy and safety of targeted temperature management with combined external cooling and neuromuscular blockade to block shivering in patients...

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Principais autores: Carl B. Shanholtz, Michael L. Terrin, Thelma Harrington, Caleb Chan, Whittney Warren, Robert Walter, Faith Armstrong, Jeffrey Marshall, Rachel Scheraga, Abjihit Duggal, Perry Formanek, Michael Baram, Majid Afshar, Nathaniel Marchetti, Sunit Singla, John Reilly, Dan Knox, Nitin Puri, Kevin Chung, Clayton H. Brown, Jeffrey D. Hasday
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2023-06-01
coleção:Contemporary Clinical Trials Communications
Assuntos:
Acute respiratory distress syndrome
Therapeutic hypothermia
Neuromuscular blockade
Randomized controlled trial
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2451865423001011
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