Characterization of a plasmid dependent DNA phage targeting Escherichia coli harboring a conjugative plasmid and its impact on gut microbiota

Abstract The emergence and spread of antimicrobial resistance in bacteria pose a significant global threat to public health. One of the main drivers of this spread is the horizontal transfer of antimicrobial resistance genes via conjugative plasmids. In this study, we isolated a novel phage, PDP46,...

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Autors principals:	Geunsoo Jung, Hyunwoo Zin, Bokyung Son, Hakdong Shin, Jinwoo Kim
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-06-01
Col·lecció:	Scientific Reports
Matèries:	Antibiotic resistance Bacteriophage Conjugation Conjugative plasmid Gut microbiota modulator Plasmid-dependent phage
Accés en línia:	https://doi.org/10.1038/s41598-025-04494-3
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