Current practice on covariate adjustment and stratified analysis —based on survey results by ASA oncology estimand working group conditional and marginal effect task force

Abstract Background The 2023 FDA's guidance on covariate adjustment encourages the judicious use of baseline covariates to enhance efficiency. However, when performing covariate adjustment in non-linear models, care must be taken on preserving estimation of the target estimand as introduced by the I...

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Auteurs principaux:	Jiawei Wei, Sarwar I. Mozumder, Liming Li, Dong Xi, Jiajun Xu, Ray Lin, Oleksandr Sverdlov, Jonathan J. Chipman, Conditional, Marginal Task Force under ASA Oncology Estimand Working Group
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2025-11-01
Collection:	BMC Medical Research Methodology
Sujets:	Covariate adjustment Stratified analysis Estimand Survey
Accès en ligne:	https://doi.org/10.1186/s12874-025-02670-7
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