C-Myc/H19/miR-29b axis downregulates nerve/glial (NG)2 expression in glioblastoma multiforme

Nerve/glial antigen (NG)2 is highly expressed in glioblastoma multiforme (GBM). However, the underlying mechanisms of its upregulated expression are largely unknown. In silico analyses reveal that the tumor-suppressive miR-29b targets NG2. We used GBM-based data from The Cancer Genome Atlas database...

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Detalhes bibliográficos

Principais autores:	Anne S. Boewe, Selina Wrublewsky, Jessica Hoppstädter, Claudia Götz, Alexandra K. Kiemer, Michael D. Menger, Matthias W. Laschke, Emmanuel Ampofo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-03-01
coleção:	Molecular Therapy: Nucleic Acids
Assuntos:	MT: Non-coding RNAs glioblastoma multiforme NG2 miR-29b PDGFRα H19
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2162253124000076
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