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Dynein Transmits Polarized Actomyosin Cortical Flows to Promote Centrosome Separation

The two centrosomes present at the onset of mitosis must separate in a timely and accurate fashion to ensure proper bipolar spindle assembly. The minus-end-directed motor dynein plays a pivotal role in centrosome separation, but the underlying mechanisms remain elusive, particularly regarding how dy...

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書誌詳細
主要な著者: Alessandro De Simone, François Nédélec, Pierre Gönczy
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2016-03-01
シリーズ:Cell Reports
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2211124716300936
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