Ha-Ras<sup>V12</sup>-Induced Multilayer Cellular Aggregates Is Mediated by Rac1 Activation Rather Than YAP Activation
We demonstrate that Ha-Ras<sup>V12</sup> overexpression induces the nuclear translocation of Hippo effector Yes-associated protein (YAP) in MDCK cells via the hippo-independent pathway at the confluent stage. Ha-Ras<sup>V12</sup> overexpression leads to the downregulation of Caveolin-1 (Cav1) and th...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI AG
2022-04-01
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| Col·lecció: | Biomedicines |
| Matèries: | |
| Accés en línia: | https://www.mdpi.com/2227-9059/10/5/977 |
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