Proinflammatory IFNγ Is Produced by but Not Required for the Generation of Eomes⁺ Thymic Innate CD8 T Cells

Innate CD8 T cells are proinflammatory effector T cells that achieve functional maturation in the thymus prior to their export into and maturation in peripheral tissues. Innate CD8 T cells produce the Th1 cytokine IFNγ but depend on the Th2 cytokine IL-4 for their generation. Thus, innate CD8 T cell...

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Autori principali:	Hee Yeun Won, Nurcin Liman, Can Li, Jung-Hyun Park
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2023-10-01
Serie:	Cells
Soggetti:	eomesodermin IFNγ IL-2Rβ <i>i</i>NKT cells thymus
Accesso online:	https://www.mdpi.com/2073-4409/12/20/2433
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