Preparation of colon-targeted pellets loaded with filgotinib/berberine hydrochloride and Their application in ulcerative colitis therapy

Ulcerative colitis (UC) is a recurrent-remitting autoimmune disease of the colon, the pathogenesis of which remains incompletely understood. Recent studies have revealed gut dysbiosis and immune imbalance mediated by the JAK-STAT and NF-κB signaling pathways are closely associated with the onset and...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Jinglong Wang, Zhixuan Kuang, Binglian Chen, Chenxi Yan, Bowen Shi, Guofei Li
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Elsevier 2025-12-01
سلاسل:	International Journal of Pharmaceutics: X
الموضوعات:	Ulcerative colitis Colon-targeted pellets Gut microbiota dysbiosis Immune imbalance Berberine hydrochloride Filgotinib
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2590156725001008
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!