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The Dual Role of Interleukin-6 in the Pathophysiology of Skeletal Muscle: Mechanisms, Challenges, and Therapeutic Prospects

Interleukin-6 (IL-6) is a cytokine with multiple biological effects. It plays a complex and seemingly paradoxical central role in both the physiological homeostasis and pathological processes of skeletal muscle. Under physiological conditions, particularly during acute exercise, IL-6 produced and se...

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Principais autores: Yingyu Wang, Jitai Zhang, Jie Wang, Yijie Zhang, Jiacheng Sun, Jiahuan Gong, Xinlei Yao, Hualin Sun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2026-05-01
coleção:Pharmaceuticals
Assuntos:
interleukin-6
skeletal muscle
myokine
muscle atrophy
therapeutic strategy
Acesso em linha:https://www.mdpi.com/1424-8247/19/6/868
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