Evaluation of phenotypic and functional stability of RAW 264.7 cell line through serial passages.

Established cell lines are widely used in research, however an appealing question is the comparability of the cells between various laboratories, their characteristics and stability in time. Problematic is also the cell line misidentification, genetic and phenotypic shift or Mycoplasma contamination...

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Main Authors: Bartłomiej Taciak, Maciej Białasek, Agata Braniewska, Zuzanna Sas, Paulina Sawicka, Łukasz Kiraga, Tomasz Rygiel, Magdalena Król
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2018-01-01
Colecção:PLoS ONE
Acesso em linha:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0198943/1/pone.0198943.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210218%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210218T053220Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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