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Phenome-wide investigation of the causal associations between childhood BMI and adult trait outcomes: a two-sample Mendelian randomization study

Abstract Background Childhood obesity is reported to be associated with the risk of many diseases in adulthood. However, observational studies cannot fully account for confounding factors. We aimed to systematically assess the causal associations between childhood body mass index (BMI) and various a...

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Autori principali: Shan-Shan Dong, Kun Zhang, Yan Guo, Jing-Miao Ding, Yu Rong, Jun-Cheng Feng, Shi Yao, Ruo-Han Hao, Feng Jiang, Jia-Bin Chen, Hao Wu, Xiao-Feng Chen, Tie-Lin Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2021-03-01
Serie:Genome Medicine
Soggetti:
Childhood BMI
Mendelian randomization
Adult outcome
Causal
Accesso online:https://doi.org/10.1186/s13073-021-00865-3
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