An adjusted droplet digital PCR assay for quantification of vector copy number in CAR-T cell and TCR-T cell products
Background: Genetically engineered T-cell therapy holds immense promise in cancer immunotherapy. These T-cell products are typically engineered by vectors that permanently integrate into the T-cell genome, thus raising concerns about potential risks of insertional mutagenesis. Therefore, it becomes...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2025-03-01
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| Serie: | Immuno-Oncology and Technology |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2590018824003289 |
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