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The pachytene-specific lncRNA 1700008K24Rik is essential for mouse spermatogenesis and functions as a conserved piRNA precursor

Spermatogenesis is a complex differentiation process requiring precise spatiotemporal gene regulation, yet the functions of most testis-enriched long noncoding RNAs (lncRNAs) remain elusive. Here, we identify 1700008K24Rik as a pachytene-specific lncRNA that is essential for mouse spermatogenesis. R...

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Gardado en:
Principais autores: Shikun Jian, Xu Han, Chenyao Xie, Yinghao Ma, Peize Chen, Weiguang Liu, Jun Xiao, Xiaoyuan Song
Formato: Artigo
Idioma:Inglês
Publicado: KeAi Communications Co., Ltd. 2026-08-01
Series:Non-coding RNA Research
Assuntos:
LncRNA
piRNA
Spermatogenesis
piRNA precursor
1700008K24Rik
TDRG1
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2468054026000326
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