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Androgen receptor monomers and dimers regulate opposing biological processes in prostate cancer cells

Abstract Most prostate cancers express the androgen receptor (AR), and tumor growth and progression are facilitated by exceptionally low levels of systemic or intratumorally produced androgens. Thus, absolute inhibition of the androgen signaling axis remains the goal of current therapeutic approache...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Rachid Safi, Suzanne E. Wardell, Paige Watkinson, Xiaodi Qin, Marissa Lee, Sunghee Park, Taylor Krebs, Emma L. Dolan, Adam Blattler, Toshiya Tsuji, Surendra Nayak, Marwa Khater, Celia Fontanillo, Madeline A. Newlin, Megan L. Kirkland, Yingtian Xie, Henry Long, Emma C. Fink, Sean W. Fanning, Scott Runyon, Myles Brown, Shuichan Xu, Kouros Owzar, John D. Norris, Donald P. McDonnell
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Portfolio 2024-09-01
سلاسل:Nature Communications
الوصول للمادة أونلاين:https://doi.org/10.1038/s41467-024-52032-y
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