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The effect of maternal BMI, smoking and alcohol on congenital heart diseases: a Mendelian randomisation study

Abstract Background Congenital heart diseases (CHDs) remain a significant cause of infant morbidity and mortality. Epidemiological studies have explored maternal risk factors for offspring CHDs, but few have used genetic epidemiology methods to improve causal inference. Methods Three birth cohorts,...

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Main Authors: Kurt Taylor, Robyn E. Wootton, Qian Yang, Sam Oddie, John Wright, Tiffany C. Yang, Maria Magnus, Ole A. Andreassen, Maria Carolina Borges, Massimo Caputo, Deborah A. Lawlor
Format: Artigo
Language:Inglês
Published: BMC 2023-02-01
Series:BMC Medicine
Subjects:
Congenital heart disease
Mendelian randomisation
Risk factors
ALSPAC, BiB
MoBa
Online Access:https://doi.org/10.1186/s12916-023-02731-y
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