Exposure–response modeling for nausea incidence for cotadutide using a Markov modeling approach

Abstract Cotadutide is a dual glucagon‐like peptide‐1 (GLP‐1)/glucagon receptor agonist. Gastrointestinal adverse effects are known to be associated with GLP‐1 receptor agonism and can be mitigated through tolerance development via a gradual up‐titration. This analysis aimed to characterize the rela...

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Bibliografski detalji

Glavni autori:	Hongtao Yu, Sebastian Ueckert, Lina Zhou, Jenny Cheng, Darren Robertson, Lars Hansen, Armando Flor, Victoria Parker, Bengt Hamrén, Anis A. Khan
Format:	Artigo
Jezik:	Inglês
Izdano:	Wiley 2024-09-01
Serija:	CPT: Pharmacometrics & Systems Pharmacology
Online pristup:	https://doi.org/10.1002/psp4.13194
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