RHOA KNOCKDOWN AFFECTS P53 SUBCELLULAR LOCALIZATION IN LEUKEMIA CELLS IRRADIATED WITH UVC
Introduction and aims: Acute myeloid leukemia (AML) is a severe hematological malignancy with low rates of survival. Mutations in the tumor suppressor gene TP53 are present in around 10% of AML cases and are associated with a worse prognosis. Evidence suggests that the Rho GTPase proteins RhoA and R...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2024-10-01
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| Serie: | Hematology, Transfusion and Cell Therapy |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2531137924009477 |
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