Integrated transcriptomic, proteomic, and metabolomic analysis unveils key roles of protein and nucleic acid interactions in diabetic ulcer pathogenesis

BackgroundDiabetes mellitus significantly increases the risk of complications, particularly diabetic foot ulcers (DFUs). However, the underlying mechanism remains unclear. This study aimed to assess the overall therapeutic approach in diabetic ulcers.MethodsUsing integrated high-throughput multi-omi...

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Principais autores:	Yongpan Lu, Hairui Gao, Sen Wang, Han Xu, Zhiyu Chen, Yixin Zhang, Yunfei Gu, Xiaomei Sun
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Endocrinology
Assuntos:	diabetic foot ulcers transcriptomics proteomics metabolomics multi-omics
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1574858/full
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