Smed-pou4-2 regulates mechanosensory neuron regeneration and function in planarians

POU4 homologs are involved in the development of sensory cell types across diverse species, including cnidarians, ascidians, and mammals. Whether these developmental regulators are redeployed during adult tissue maintenance and regeneration remains an open question in regenerative biology. Here, we...

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Bibliographic Details
Main Authors: Ryan A McCubbin, Mohammad A Auwal, Shengzhou Wang, Sarai Alvarez Zepeda, Roman Sasik, Robert W Zeller, Kelly G Ross, Ricardo M Zayas
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications Ltd 2025-11-01
Series:eLife
Subjects:
POU4 transcription factor
ciliated sensory neurons
mechanosensation
gene regulatory networks
terminal selector
Online Access:https://elifesciences.org/articles/107718
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