An ACE2 PET imaging agent derived from 18F/Cl exchange of MLN-4760 under phase transfer catalysis

Abstract Background Angiotensin-converting enzyme-2 (ACE2) acts as a key regulatory molecule and important therapeutic target in the pathological remodeling of numerous organs and diseases. In this study, a rapid, simple, and efficient synthetic route with a catalytic, 18F-for-Cl (18F/Cl) exchange s...

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Detalhes bibliográficos

Principais autores:	Pan Zhou, Kai Ning, Shuai Xue, Qingqing Li, Danni Li, Haijun Yang, Zeying Liang, Rou Li, Jian Yang, Xiao Li, Lan Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SpringerOpen 2024-12-01
coleção:	EJNMMI Radiopharmacy and Chemistry
Assuntos:	MLN−4760 ACE2 18F/Cl exchange PET imaging agent Phase transfer catalysis
Acesso em linha:	https://doi.org/10.1186/s41181-024-00316-5
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